Apolipoprotein C-III Bound to Apolipoprotein B-containing Lipoproteins in Obese Girls

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Apolipoprotein C-III bound to apolipoprotein B-containing lipoproteins in obese girls.

taining Lipoproteins in Obese Girls, Piers R. Blackett, Robin Germany, Boureima Sambo, and Petar Alaupovic, ( Department of Pediatrics, 2 University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104; 3 Medical Research Foundation, Oklahoma City, OK 73109; * address correspondence to this author at: Children’s Hospital of Oklahoma, Room 2426, 940 NE 13th St., Oklahoma City, OK 73104; f...

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Comparison of four procedures for separating apolipoprotein A- and apolipoprotein B-containing lipoproteins in plasma.

Because lipoproteins containing apolipoprotein A (ApoA-I + ApoA-II) or apolipoprotein B (ApoB) seem to exert opposite effects as risk factors for coronary heart disease, we decided to determine the separability of these two major plasma lipoproteins by procedures originally designed to separate high-density from low- and very-low-density lipoproteins. The presumably ApoB-free lipoproteins isola...

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Lipoprotein lipase bound to apolipoprotein B lipoproteins accelerates clearance of postprandial lipoproteins in humans.

OBJECTIVE Experiments in cells and animal models show that lipoprotein lipase (LpL) bound to apolipoprotein (apo)B lipoproteins enhances their uptake by receptor mediated pathways. It is unknown whether this pathway is important in humans. METHODS AND RESULTS ApoB lipoproteins with LpL were isolated from normal subjects after oral fat loading by immunoaffinity chromatography and were further ...

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Apolipoprotein B-containing lipoproteins and atherosclerotic cardiovascular disease

Cholesterol-rich, apolipoprotein B (apoB)-containing lipoproteins are now widely accepted as the most important causal agents of atherosclerotic cardiovascular disease. Multiple unequivocal and orthogonal lines of evidence all converge on low-density lipoprotein and related particles as being the principal actors in the genesis of atherosclerosis. Here, we review the fundamental role of atherog...

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RATIONALE Plasma apolipoprotein (apo)M is mainly associated with high-density lipoprotein (HDL). HDL-bound apoM is antiatherogenic in vitro. However, plasma apoM is not associated with coronary heart disease in humans, perhaps because of a positive correlation with plasma low-density lipoprotein (LDL). OBJECTIVE We explored putative links between apoM and very-low-density (VLDL)/LDL metabolis...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 2003

ISSN: 0009-9147,1530-8561

DOI: 10.1373/49.2.303